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Analysis

1.WO/2020/138265METHOD, APPARATUS AND PROGRAM FOR ASSESSING AMYLOID FORMATION
WO 02.07.2020
Int.Class G01N 21/64
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
Appl.No PCT/JP2019/051077 Applicant NATIONAL UNIVERSITY CORPORATION MURORAN INSTITUTE OF TECHNOLOGY Inventor TOKURAKU Kiyotaka
The present invention pertains to: a method for determining amyloid formation inhibitory activities of test substances, the method comprising: a step for reacting, in the presence or absence of a test substance, an amyloidogenic protein with a fluorescent probe capable of binding to amyloid formed by polymerizing the amyloidogenic protein; a step for capturing the fluorescence of agglutination reaction products under an exposure condition in which Sum Intensity calculated from the brightness value of each pixel included in a region of interest in a fluorescence image to be captured is 15-85%; a step for calculating the standard deviation from the brightness value of each pixel included in the region of interest in the captured fluorescence image; and a step for comparing the calculated standard deviation in brightness values in the presence of the test substance and the standard deviation in brightness values in the absence of the test substance, and determining that the test substance has an amyloid formation inhibitory activity when the standard deviation in brightness values in the presence of the test substance is smaller than the standard deviation in brightness values in the absence of the test substance; and an apparatus and a program which can be used in implementing the method.
2.WO/2020/138478METHOD FOR ANALYZING AND DIAGNOSING STATES RELATED TO METASTASIS/PRIMARY ONSET OF CANCER USING RNA MODIFICATION
WO 02.07.2020
Int.Class C12Q 1/6809
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6809Methods for determination or identification of nucleic acids involving differential detection
Appl.No PCT/JP2019/051560 Applicant OSAKA UNIVERSITY Inventor KONNO Masamitsu
The present disclosure provides a new method for analyzing states related to the metastasis/primary onset of cancer in a subject. The present disclosure provides a new method for analyzing states related to the metastasis/primary onset of cancer in a subject (for example, whether a subject has metastatic cancer, and whether a cancer is primary), on the basis of the discovery that cancer metastatic states are reflected in RNA modification information. The present disclosure makes it possible to analyze various biological states including cancer metastasis, and also makes it possible to determine the cancer to be treated as well as select a suitable treatment method.
3.WO/2020/138709METHOD FOR ANALYZING SILICON CONCENTRATION IN PHOSPHORIC ACID SOLUTION
WO 02.07.2020
Int.Class G01N 25/14
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
25Investigating or analysing materials by the use of thermal means
14by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
Appl.No PCT/KR2019/015261 Applicant SEMIBOOSTER CO.,LTD. Inventor LEE, Seung Hun
The present invention relates to a method for analyzing the concentration of silicon by using the solubility of silicon in a phosphoric acid solution to analyze the concentration of silicon generated in the process of etching silicon nitride. The method for analyzing silicon concentration of the present invention has an effect of providing a method capable of analyzing only the concentration of silicon generated in the phosphoric acid process of etching silicon nitride, and optionally capable of analyzing the concentration of a silicon compound added to increase selectivity.
4.WO/2020/138764REFERENCE CASSETTE FOR FLUORESCENCE IMMUNOASSAY DIAGNOSTIC DEVICE
WO 02.07.2020
Int.Class G01N 21/64
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
Appl.No PCT/KR2019/017352 Applicant PRECISION BIOSENSOR INC. Inventor KIM, Hee Jun
Provided in the present invention is a reference cassette for a fluorescence immunoassay diagnostic device, the cassette having, arranged in a case, fluorescent glass capable of maintaining fluorescence characteristics to be constant without causing degeneration, so as to accurately provide reference measurement information about the fluorescence detection amount during testing of the measurement accuracy of the fluorescence detection of the immunoassay diagnostic device, so that testing accuracy can improve, preventing decrease in measurement accuracy and being semi-permanently usable since the denaturation or deterioration of the fluorescent glass does not occur even if the cassette is used continuously, and providing a mask having a slit so as to limit the area of the fluorescent glass to be externally exposed to a specific area, thereby generating the type of fluorescence that is the same as that of a reaction area of a sample strip to be actually used, and thus more accurate reference measurement information can be provided.
5.WO/2020/139229A MICROFLUIDIC DEVICE FOR SELECTIVE CAPTURE OF BIOLOGICAL ENTITIES
WO 02.07.2020
Int.Class B01L 3/00
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
Appl.No PCT/TR2019/050649 Applicant MIKRO BIYOSISTEMLER ELEKTRONIK SANAYI VE TICARET A.S. Inventor SEN DOGAN, Begum
This invention based on a microfluidic device that is used for in vitro selective capture of biological entities suspended in a medium based on immunoaffinity technique. The device includes symmetric hydrofoil pillars arranged inside ellipse segments acting as microfluidic channel which provides continuous change of attack angles between the pillars and biological entities.
6.WO/2020/139351MEASURING THE OIL CONTENT IN OIL-BASED DRILLING FLUIDS
WO 02.07.2020
Int.Class E21B 49/00
EFIXED CONSTRUCTIONS
21EARTH OR ROCK DRILLING; MINING
BEARTH OR ROCK DRILLING; OBTAINING OIL, GAS, WATER, SOLUBLE OR MELTABLE MATERIALS OR A SLURRY OF MINERALS FROM WELLS
49Testing the nature of borehole walls; Formation testing; Methods or apparatus for obtaining samples of soil or well fluids, specially adapted to earth drilling or wells
Appl.No PCT/US2018/067702 Applicant HALLIBURTON ENERGY SERVICES, INC. Inventor YE, Xiangnan
Systems and methods for measurement of the oil content in oil-based drilling may be provided in accordance with embodiments of the present disclosure. A method for measuring oil content of an oil-based drilling fluid may include providing a sample of the oil-based drilling fluid. The method may further include performing electro impedance spectroscopy on the sample by a process that comprises applying an alternating electric current to the sample and measuring a response of sample to obtain electro impedance spectroscopy measurements. The method may further include determining an estimate of the oil content of the sample based, at least partially on the electro impedance spectroscopy measurements.
7.WO/2020/139430QUANTITATIVE LARGE AREA BINDING SENSOR FOR DETECTING BIOMARKERS
WO 02.07.2020
Int.Class G01N 15/14
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
14Electro-optical investigation
Appl.No PCT/US2019/053530 Applicant ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA Inventor XIONG, Zhen
An imaging system and method for detecting a target in a sample. The imaging system includes a lens-free holographic microscope having a light source in a first plane spaced above an image sensor. The image sensor extends in a second plane. The system also includes a microfluidic chip positioned between the light source and the image sensor. The microfluidic chip extends in a third plane, which is parallel to the second plane. There is at least one chamber in the microfluidic chip configured to receive a sample solution with a target. The system also has a plurality of functionalized beads positioned within the at least one chamber in the microfluidic chip. Any two of the plurality of functionalized beads have an affinity for binding together when exposed to the target in the sample solution.
8.WO/2020/139495LOW VOLUME EXTRACORPOREAL PHOTOPHERESIS SYSTEMS AND METHODS
WO 02.07.2020
Int.Class A61M 1/38
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
38Removing constituents from donor blood and returning remainder to body
Appl.No PCT/US2019/062730 Applicant FENWAL, INC. Inventor RADWANSKI, Katherine N.
Systems and methods for performing low volume (e.g., 500 mL or less) extracorporeal photopheresis (ECP) procedures are disclosed. Each of the different systems and methods eliminates the need for multiple kits and solutions and reduce some of the potential risks inherent in the use of such multiple kits and solutions.
9.WO/2020/139515METHOD FOR DETERMINING THE COMPOSITION AND PROPERTIES OF HYDROCARBON FRACTIONS BY SPECTROSCOPY OR SPECTROMETRY
WO 02.07.2020
Int.Class G01N 21/359
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
35using infra-red light
359using near infra-red light
Appl.No PCT/US2019/063819 Applicant SAUDI ARABIAN OIL COMPANY Inventor KOSEOGLU, Omer, Refa
This invention relates to a system and method for the evaluation of samples of a distillate fraction by spectroscopic analysis, followed by the application of chemometrics software to determine physical characteristics of the fraction.
10.WO/2020/139620BIOMARKERS OF NEUTROPHIL DEREGULATION AS DIAGNOSTIC FOR GINGIVITIS
WO 02.07.2020
Int.Class G01N 33/569
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
569for microorganisms, e.g. protozoa, bacteria, viruses
Appl.No PCT/US2019/066813 Applicant COLGATE-PALMOLIVE COMPANY Inventor ZENOBIA, Camille
Methods of determining one or more ratios of chemokines in gingival crevicular fluid of an individual selected from the group consisting of: MIF:MIP1a, MIF:CXCL1; MIF:CXCL5; MIF:CXCL8; MIF:CXCL2; and MIF:CXCL6 and methods of identifying an individual as having gingivitis comprising determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Methods of treating individuals who are identified as having gingivitis by determining one or more ratios of the chemokines in gingival crevicular fluid are disclosed. Also disclosed are methods of monitoring the treatment individuals who have gingivitis.