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Analysis

1.20200368262Use of Timosaponin Enzymatically Transformed Product in Preparation of Drugs for Inhibiting Skin Superficial Fungi
US 26.11.2020
Int.Class A61K 31/7048
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7048having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
Appl.No 16848708 Applicant Shanghai University of Traditional Chinese Medicine Inventor Tong ZHANG

The present disclosure provides use of a timosaponin enzymatically transformed product in preparation of drugs for inhibiting skin superficial fungi. In the use provided in the present disclosure, the timosaponin enzymatically transformed product is prepared by enzymatically transforming rhizoma anemarrhenae extract with β-glucosidase or a compound enzyme of xylanase and cellulose after purification. In the present disclosure, as an active pharmaceutical ingredient for inhibiting skin superficial fungi, the timosaponin enzymatically transformed product has the minimum inhibitory concentration of 4 mg/L against fungi, which is obviously superior to total timosaponin in the bacteriostatic capability, and has a certain application prospect in the aspect of treating skin superficial mycoses.

2.20200370082METHOD FOR PREPARING ISOMALTOOLIGOSACHARIDE COMPOSITION
US 26.11.2020
Int.Class C12P 19/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
24produced by the action of an isomerase, e.g. fructose
Appl.No 16959626 Applicant CORN PRODUCTS DEVELOPMENT, INC. Inventor HEA-SEOK JEONG

This invention provides an isomaltooligosaccharide (IMO) composite and the method to manufacture. According to this invention, isomaltooligosaccharide with a high level of sweetness can be provided without an additional process of adding fructose.

3.20200369982PROCESS FOR PRODUCTION OF CONCENTRATED POLYUNSATURATED FATTY ACID OILS
US 26.11.2020
Int.Class C11C 3/00
CCHEMISTRY; METALLURGY
11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
CFATTY ACIDS OBTAINED FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS OBTAINED BY CHEMICAL MODIFICATION OF FATS, OILS OR FATTY ACIDS
3Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis
Appl.No 16636938 Applicant DSM IP Assets B.V. Inventor Jaroslav KRALOVEC

The present invention relates to oil compositions that are enriched in polyunsaturated fatty acids; compositions containing the oil compositions; and methods of making and using the oil compositions. The oil is preferably a microbial or marine oil.

4.20200370072MICROORGANISM AND METHOD FOR IMPROVED 1,3-PROPANEDIOL PRODUCTION BY FERMENTATION ON A CULTURE MEDIUM WITH HIGH GLYCERINE CONTENT
US 26.11.2020
Int.Class C12P 7/18
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
02containing a hydroxy group
04acyclic
18polyhydric
Appl.No 16636237 Applicant METABOLIC EXPLORER Inventor Céline RAYNAUD

The present invention concerns a new method for the production of 1,3-propanediol comprising culturing a recombinant microorganism converting glycerol into 1,3-propanediol and overexpressing the hcpR and/or frdX gene on a medium comprising glycerine. A recombinant microorganism for the production of 1,3 propanediol from glycerol, wherein said microorganism converts glycerol into 1,3-propanediol and 10 overexpresses the hcpR and/or the frdX gene.

5.WO/2020/234287METHOD FOR PREPARING A PEPTIDE SAMPLE
WO 26.11.2020
Int.Class G01N 33/68
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
Appl.No PCT/EP2020/063944 Applicant CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER Inventor LEHMANN, Sylvain
The present application relates to a method for preparing a peptide sample from a biological sample, and to a method for detecting or quantifying proteins comprising said method for preparing a sample. The invention also relates to the use of these methods for the detection or monitoring of a condition or a disease.
6.WO/2020/233506METHOD FOR IMPROVING PRODUCTION OF STREPTOMYCES POLYKETIDE COMPOUNDS
WO 26.11.2020
Int.Class C12P 17/18
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
18containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
Appl.No PCT/CN2020/090452 Applicant EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY Inventor ZHANG, Lixin
A method for improving the production of streptomyces polyketide compounds is provided. The method greatly improves the capability of the streptomyces polyketide compounds by strengthening a triacylglycerol decomposition pathway in streptomyces during the stationary phase. A method for switching the primary metabolism of streptomyces to the secondary metabolism, streptomyces producing polyketide compounds, and use thereof are also provided.
7.WO/2020/235946USE OF ENZYME THAT CLEAVES BOTH ALPHA- AND BETA-1,4-GLYCOSIDIC BONDS
WO 26.11.2020
Int.Class C12N 9/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
24acting on glycosyl compounds (3.2)
Appl.No PCT/KR2020/006649 Applicant KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION Inventor KIM, Kyoung Heon
The present invention relates to use of an enzyme that cleaves both alpha- and beta-1,4-glycosidic bonds and, more particularly, the present invention provides α-L-fucosidase which has α-1,4-glucosidase and β-1,4-galactosidase activities and thus is capable of producing glucose and/or galactose, which are monosaccharides, from non-fucosylated saccharides. The enzyme has transglycosylation activity and thus produces maltooligosaccharides having a higher degree of polymerization than maltooligosaccharides used as a substrate, thereby being applicable to the development of high-value-added new materials in the food industry.
8.20200369811PROCESS FOR PRODUCING AQUEOUS POLYACRYLAMIDE SOLUTIONS
US 26.11.2020
Int.Class C08F 220/56
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
220Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide, or nitrile thereof
02Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
52Amides or imides
54Amides
56Acrylamide; Methacrylamide
Appl.No 16759244 Applicant BASF SE Inventor Tobias Joachim ZIMMERMANN

Process for producing aqueous polyacrylamide solutions by polymerizing an aqueous solution comprising at least acrylamide obtained by hydrolyzing acrylonitrile in water in the presence of a biocatalyst capable of converting acrylonitrile to acrylamide thereby obtaining an aqueous polyacrylamide gel and dissolving said aqueous polyacrylamide gel in water, wherein the manufacturing steps are allocated to two different locations A and B and the process comprises the step of transporting an aqueous polyacrylamide gel hold in a transportable polymerization unit from a location A to a location B. The aqueous polyacrylamide gel furthermore comprises at least one stabilizer for prevention of polymer degradation.

9.20200370071BIOCHEMICAL UPGRADING OF HIGH-PROTEIN BIOMASS AND GRAIN PRODUCTS
US 26.11.2020
Int.Class C12P 7/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
7Preparation of oxygen-containing organic compounds
02containing a hydroxy group
04acyclic
16Butanols
Appl.No 16868670 Applicant National Technology & Engineering Solutions of Sandia, LLC Inventor Ryan Wesley Davis

The present invention relates to methods of upgrading biomass to provide useful chemical intermediates, fuels, amino acids, nutrients, etc. In particular examples, the biomass is a by-product of ethanol production and is mainly used as high-protein feed. Described herein are methods for upgrading such biomass, such as by implementing pre-treatment conditions and by employing fermentation conditions including modified organisms.

10.20200370081BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS
US 26.11.2020
Int.Class C12P 17/16
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
17Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms
16containing two or more hetero rings
Appl.No 16966359 Applicant The Regents of the University of Michigan Inventor Haoming ZHANG

The present invention relates to methods for synthesizing mixed disulfide conjugates of thienopyridine compounds with a genetically engineered variant of cytochrome P450 BM3 or CYP102A1 as a catalyst, and belongs to the field of chemical synthesis.