Processing

Please wait...

Settings

Settings

Goto Application

Offices all Languages en Stemming true Single Family Member true

Save query

A private query is only visible to you when you are logged-in and can not be used in RSS feeds

Query Tree

Refine Options

Offices
All
Specify the language of your search keywords
Stemming reduces inflected words to their stem or root form.
For example the words fishing, fished,fish, and fisher are reduced to the root word,fish,
so a search for fisher returns all the different variations
Returns only one member of a family of patents

Full Query

IC:C12N7/00

Side-by-side view shortcuts

General
Go to Search input
CTRL + SHIFT +
Go to Results (selected record)
CTRL + SHIFT +
Go to Detail (selected tab)
CTRL + SHIFT +
Go to Next page
CTRL +
Go to Previous page
CTRL +
Results (First, do 'Go to Results')
Go to Next record / image
/
Go to Previous record / image
/
Scroll Up
Page Up
Scroll Down
Page Down
Scroll to Top
CTRL + Home
Scroll to Bottom
CTRL + End
Detail (First, do 'Go to Detail')
Go to Next tab
Go to Previous tab

Analysis

1.WO/2020/139279ACINETOBACTER BAUMANNII BACTERIOPHAGE MIKAB48 OR LYTIC PROTEIN DERIVED FROM THE BACTERIOPHAGE
WO 02.07.2020
Int.Class C12N 7/00
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
Appl.No PCT/TR2019/051177 Applicant MIKROLIZ BIYOTEKNOLOJI SAN. VE TIC. LTD. STI. Inventor COTAK, Medine
The invention discloses a novel Acinetobacter baumannii bacteriophage and lytic protein derived from the bacteriophage. The bacteriophage and lytic protein derived from the bacteriophage both have strong in vitro antibacterial effects on pan-drug resistant Acinetobacter baumannii clinical strains providing experimental basis for developing a preparation for preventing and treating infections caused by Acinetobacter baumannii containing the bacteriophage or lytic protein thereof.
2.WO/2020/137421HOST BACTERIUM SPECIFIC NANOPARTICLE
WO 02.07.2020
Int.Class A61P 1/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
Appl.No PCT/JP2019/047649 Applicant GIFU UNIVERSITY Inventor MITSUNAKA Shoichi
The present invention addresses the issue of providing a recombinant phage that is highly safe and has excellent practicality and usefulness. Provided are: a recombinant bacteriophage that has lost proliferative capacity and can only infect once, as a result of having a bacteriophage genome having part of a virion-constituting gene deleted therefrom stored in the head thereof; and a preparation method therefor. Also provided are: a recombinant bacteriophage that has lost proliferative capacity and can only infect once, as a result of having a plasmid having a packaging site and coding a target gene stored in the head thereof; and a preparation method therefor.
3.WO/2020/135108DUCK PLAGUE VIRUS GE AND GI DUAL-GENE TRACELESS DELETION STRAIN DPV CHV-DELTA GE + DELTA GI AND CONSTRUCTION METHOD THEREFOR
WO 02.07.2020
Int.Class C12N 7/01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
01Viruses, e.g. bacteriophages, modified by introduction of foreign genetic material
Appl.No PCT/CN2019/125291 Applicant SICHUAN AGRICULTURAL UNIVERSITY Inventor CHENG, Anchun
Provided are a duck plague virus gE and gI dual-gene traceless deletion strain DPV CHv-delta gE + delta gI and a construction method therefor. A duck plague virus gE gene and a duck plague virus gI gene are deleted by means of two times of homologous recombination on a bacterial artificial chromosome recombination duck plague virus rescue system platform by using a GS1783 escherichia coli strain and a pEPkan-S plasmid, a MiniF element is deleted by using an intracellular spontaneous homologous recombination method, and thus the construction of a duck plague virus dual-gene traceless deletion strain free from exogenous base and MiniF element residue is completed for the first time.
4.WO/2020/140012LYOPHILIZED VIRUS FORMULATIONS
WO 02.07.2020
Int.Class A61K 9/19
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
19lyophilised
Appl.No PCT/US2019/068700 Applicant AMGEN INC. Inventor FLOOD, Enrique, Alexander
Provided herein is a powder comprising a live, attenuated virus, recombinant human serum albumin (rHSA), a sugar other than lactose, a sugar alcohol, a source of phosphate, a source of chloride, wherein the composition is substantially free of lactose, gelatin, antibiotic, and free amino acids. In exemplary aspects, the powder is a lyophilizate of a liquid composition. Related liquid compositions, methods of preparing an oncolytic virus for administration and methods of treating melanoma are also provided herein.
5.WO/2020/135390ONCOLYTIC VIRUS EXPRESSING INTERFERON AND APPLICATION THEREFOR
WO 02.07.2020
Int.Class C12N 7/01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
7Viruses, e.g. bacteriophages; Compositions thereof; Preparation or purification thereof
01Viruses, e.g. bacteriophages, modified by introduction of foreign genetic material
Appl.No PCT/CN2019/127782 Applicant SHANGHAI YUANSONG BIOTECHNOLOGY CO. LTD. Inventor ZHANG, Kangjian
Provided is an oncolytic virus expressing an interferon. Specifically provided is an oncolytic adenovirus expressing an interferon hybrid protein, said oncolytic virus being capable of effectively suppressing tumors in vitro and in vivo.
6.WO/2020/136154NON-REPLICATIVE TRANSDUCTION PARTICLES AND TRANSDUCTION PARTICLE-BASED REPORTER SYSTEMS FOR DETECTION OF ACINETOBACTER BAUMANNII
WO 02.07.2020
Int.Class C12Q 1/6897
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6897involving reporter genes operably linked to promoters
Appl.No PCT/EP2019/086887 Applicant F. HOFFMANN-LA ROCHE AG Inventor DUNPHY, Kathleen Y.
The present invention relates to novel bacteriophages that are specific for Acinetobacter baumannii (A. baumannii) and to methods for producing non-replicative transduction particles (NRTPs) derived from these bacteriophages and to the use of the NRTPs for detection of A. baumannii.
7.WO/2020/134924DUCK PLAGUE VIRUS GC GENE-DELETION STRAIN DPV CHV-ΔGC WITH MINIF ELEMENT REMOVED AND CONSTRUCTION METHOD THEREFOR
WO 02.07.2020
Int.Class C12N 15/63
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
Appl.No PCT/CN2019/122997 Applicant SICHUAN AGRICULTURAL UNIVERSITY Inventor CHEN, Anchun
Disclosed are a duck plague virus gC gene-deletion strain DPV CHv-ΔgC with a MiniF element removed and a construction method therefor. By using a GS1783 E. coli strain and a pEPKan-S plasmid, a MiniF element is deleted from a bacterial artificial chromosome recombinant duck plague virus rescuing system platform by means of an intracellular spontaneous homologous recombination method, such that the present invention finishes the construction of a duck plague virus traceless deletion strain without MiniF element residues for the first time, solves the problem that the MiniF element remains in a duck plague virus genome when a duck plague virus gene is deleted, and provides sufficient technical support for accurately exploring the functions of the duck plague virus gene and constructing attenuated live vaccines.
8.WO/2020/133772METHOD AND SYSTEM FOR PREPARING RECOMBINANT ADENO-ASSOCIATED VIRUS, AND RECOMBINANT BACMID
WO 02.07.2020
Int.Class C12N 15/866
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
866Baculoviral vectors
Appl.No PCT/CN2019/080295 Applicant WUHAN INSTITUTE OF PHYSICS AND MATHEMATICS, CHINESE ACADEMY OF SCIENCES Inventor WU, Yang
Provided are a method and a system for preparing a recombinant adeno-associated virus (rAAV), and a recombinant bacmid. The method comprises: (1) respectively preparing a shuttle plasmid and a corresponding recombinant bacmid containing baculovirus genome; (2) integrating a rAAV core expression element carrying a heterologous functional gene segment with other expression cassettes of functional protein components necessary for rAAV production to obtain a recombinant bacmid containing the recombinant baculovirus genomes that produce rAAV; and (3) transfecting the recombinant bacmid into a host cell line for cultivation. The system comprises a shuttle plasmid and a corresponding recombinant bacmid containing baculovirus genome. The recombinant bacmid comprises at least one expression cassette for a functional protein component required to produce rAAV.
9.WO/2020/138761CHIMERIC VIRUS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS, AND VACCINE USING SAME
WO 02.07.2020
Int.Class C07K 14/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
Appl.No PCT/KR2019/017319 Applicant BIOPOA, INC. Inventor CHO, Sun-Hee
The present invention relates to a chimeric virus of porcine reproductive and respiratory syndrome (PRRS) virus, the chimeric virus being usable as a vaccine. A PRRSV chimeric virus of the present invention is more attenuated than the parent strain thereof, and thus promotes the secretion of neutralizing antibodies while having low pathogenicity and high stability, thereby being usable as a vaccine in the effective prevention and treatment of PRRS diseases.
10.WO/2020/136235M2-DEFECTIVE POXVIRUS
WO 02.07.2020
Int.Class A61K 39/275
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
12Viral antigens
275Poxviridae, e.g. avipoxvirus
Appl.No PCT/EP2019/087063 Applicant TRANSGENE SA Inventor KLEINPETER, Patricia
The present invention is in the field of oncolytic viruses. The invention provides new poxviruses which are engineered to be defective for the function encoded by the M2L locus (i.e., m2 function). Such poxviruses lack a functional m2 binding activity to at least one or both of CD80 and CD86 co-stimulatory antigens. Said oncolytic poxviruses are preferably vaccinia virus having a total or partial deletion of the M2L locus. The present invention also relates to cells and compositions comprising such poxviruses and their use for treating proliferative diseases such as cancers and for preventing diseases (vaccination, especially in veterinary field). More precisely, the invention provides an alternative to the existing oncolytic viruses which are largely used in virotherapy. The m2-defective poxviruses are particularly useful for the expression of immunomodulatory polypeptides such as anti-CTLA-4 antibodies with the purposes of stimulating or improve immune response.