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Analysis

1.20200368412Centrifugal Separation And Collection Of Red Blood Cells, Plasma, Or Both Red Blood Cells And Plasma
US 26.11.2020
Int.Class A61M 1/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
02Blood transfusion apparatus
Appl.No 16878653 Applicant Fenwal, Inc. Inventor Benjamin E. Kusters

Systems and methods are provided for separating blood into two or more components for collection of red blood cells, plasma, or both red blood cells and plasma. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit, with the blood being separated into its constituents by the centrifugal separator. Separated plasma may be collected following separation by the centrifugal separator or may first be conveyed from the centrifugal separator into the spinning membrane separator drive unit to separate cellular blood components from the plasma prior to collection of the filtered plasma. The cellular blood components filtered from the plasma may be retained in the circuit as a waste product or may be flushed out of the circuit to a recipient.

2.20200368422Magnetically Activated Arteriovenous Access Valve System and Related Methods
US 26.11.2020
Int.Class A61M 1/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
Appl.No 16988998 Applicant Diaxamed LLC Inventor James S. Johnson

In one aspect, an arteriovenous access valve system may generally include a first valve configured to be positioned at or adjacent to an end of an arteriovenous graft and a second valve configured to be positioned at or adjacent to an opposite end of the arteriovenous graft. In addition, the system may include an actuator assembly in fluid communication with the first and second valves. The actuator assembly may include a housing, a driver assembly positioned within the housing and a drive magnet positioned within the housing. The drive magnet may be rotatably coupled to the driver assembly such that, when the drive magnet is rotated, the driver assembly is configured to be rotatably driven so as to supply fluid to the first and second valves or to draw fluid out of the first and second valves depending on a rotational direction of the driver assembly.

3.20200371172Systems and Methods for Using Improved Contrast Agent in Performing and MRI
US 26.11.2020
Int.Class G01R 33/28
GPHYSICS
01MEASURING; TESTING
RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
33Arrangements or instruments for measuring magnetic variables
20involving magnetic resonance
28Details of apparatus provided for in groups G01R33/44-G01R33/6496
Appl.No 16363933 Applicant Ronald Day Inventor Ronald Day

The present invention relates to the use of a formation agent, such as nitric oxide or sodium nitrite to produce methemoglobin as an alternative MRI contrast agent. The formation agent can be infused using either a respiratory system or a delivery mechanism. One embodiment of this invention relates to systems and methods for producing an image of an internal region with a magnetic resonance scanning system. Blood is drawn from the patient. The blood is exposed to formation agent through a delivery system, to produce blood that has a higher saturation of methemoglobin. Where in vitro techniques are used the treated blood is injected back into the patient. The patient is scanned in the magnetic resonance scanner. These systems and methods can be used to produce images of regions which may not otherwise be possible with other contrasting agents. For example, an accurate vascular brain MRI may not be as informative if the patient is injected with an existing contrasting agent. In addition, an alternate embodiment of the invention relates to internally exposing the blood to the formation agent by placing the gas-permeable membrane along a particular blood pathway or intravenous sodium nitrite.

4.WO/2020/234407PRESSURE MEASUREMENT IN THE EXTRACORPOREAL BLOOD CIRCUIT
WO 26.11.2020
Int.Class A61M 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
16with membranes
Appl.No PCT/EP2020/064175 Applicant B. BRAUN AVITUM AG Inventor AHMED, Fakher
The invention relates to a method for calibrating a first pressure sensor (PA), which measures a first pressure in the form of a force signal within a hose (1) filled with liquid and which bears directly against the hose and is integrated into a first clamping fixture for the correction of a drift signal caused by the hose by a correction function with the aid of a pressure reference signal, which is acquired by a first pressure reference sensor (PHOP). The method comprises the following steps: a) recursive analysis and forecasting of at least one correction function for finding a correction signal for the correction of the drift signal with the aid of a corresponding pressure reference signal, which is measured by the first pressure reference sensor, at constant internal pressure and constant internal temperature in the hose; b) first calibration of the force signal measured by the first pressure sensor and corrected with the aid of the correction signal with the pressure reference signal, which is measured by the first pressure reference sensor, prior to an active use of the hose; and c) second calibration of the force signal measured by the first pressure sensor and corrected with the aid of the correction signal with the pressure reference signal, which is measured by a second pressure reference sensor (PV) during an active use of the hose. The invention further relates to a device designed for the application of a method of this kind.
5.WO/2020/236377AUTO ADJUSTMENT OF BLOOD TREATMENT PARAMETERS BASED ON PATIENT COMFORT
WO 26.11.2020
Int.Class A61M 1/16
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
16with membranes
Appl.No PCT/US2020/029136 Applicant FRESENIUS MEDICAL CARE HOLDINGS, INC. Inventor YUDS, David
A blood treatment machine includes a patient comfort feedback mechanism configured to be adjusted by a patient to indicate comfort levels of the patient. The machine is configured to adjust one or more treatment parameters based on the patient feedback.
6.20200368011STENT TO ASSIST IN ARTERIOVENOUS FISTULA FORMATION
US 26.11.2020
Int.Class A61F 2/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
2Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
02Prostheses implantable into the body
04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
06Blood vessels
Appl.No 16992808 Applicant The Board of Regents of the University of Nebraska Inventor Marius C. Florescu

There is described an arteriovenous fistula stent, having a tubular body comprising a series of sinusoidal shaped struts along the length of the tubular body. A plurality of curvilinear connectors extend between and are attached to adjacent struts wherein a first end of a connector is attached to a distal face of a proximal strut apex and a second end of a connector is attached to a proximal face of a distal strut apex. A pair of unconnected strut apexes are between pairs of connected apexes. When the tubular body is in a stowed configuration a proximal aperture and a distal aperture are circular and when the tubular body is in a deployed configuration the distal aperture is oblong or ovoid. There is also described a method for inserting a stent for use in creation of an arteriovenous fistula by identifying a candidate artery and a candidate vein and dissecting the candidate vein. Next, inserting a stent into the vein and creating a breach in the candidate artery at a desired angle and location. Next, introducing the stent and vein into the candidate artery and forming the stent into a curvature angle selected to minimize turbulent blood flow in an anastomosis formed by the vein and the artery. Optionally, there is a step of fastening a distal portion of the stent to the artery.

7.20200368411A Bioprocessing System
US 26.11.2020
Int.Class A61M 1/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
02Blood transfusion apparatus
Appl.No 16767403 Applicant Biosafe S.A. Inventor Julien Camisani

Disclosed is a bioprocessing system comprising apparatus (200) including a centrifugal separation housing (210) having a temperature controllable compartment (215) for removably accepting a separation chamber (50), the apparatus further comprising at least one mixing station (250) for supporting one or more fluid storage vessels (10, 20, 30, 40), the station including a temperature controllable area (252) for increasing or decreasing the temperature of the contents of the or each supported vessel. The system further includes a disposable fluidic arrangement (100) including a centrifugal separation chamber (50) removably mountable within the compartment (215) and having one or more ports (52) allowing fluid ingress into, or egress out of the chamber, via the one or more ports in use, said ports being in fluid communication with one or more of said fluid storage vessels via fluid conduits (12, 22, 32, 42) and via one or more valve arrangements

8.20200368421DRUG DIFFUSING PERITONEAL DIALYSIS CATHETER
US 26.11.2020
Int.Class A61M 1/28
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
14Dialysis systems; Artificial kidneys; Blood oxygenators
28Peritoneal dialysis
Appl.No 16421743 Applicant Baxter International Inc. Inventor Mark Perry

A peritoneal dialysis catheter includes: a catheter tube defining a lumen for carrying peritoneal dialysis fluid to at least one aperture located at or near a distal end of the lumen; at least one cuff located along the outside of the catheter tube; an access site proximally spaced from the at least one cuff, the access site allowing an antimicrobial agent to be introduced into the catheter tube; a reservoir operable with the catheter tube and in fluid communication with the access site, the reservoir storing an amount of the antimicrobial agent received from the access site after an antimicrobial agent introducer is removed from the access site; and a delivery area of the catheter tube in fluid communication with the reservoir, the delivery area positioned so as to target delivery of the antimicrobial agent to the at least one cuff or other desired location along the catheter tube.

9.WO/2020/235986FILTER FOR COLLECTING, PROCESSING AND INJECTING A GRAFT OF FATTY TISSUE
WO 26.11.2020
Int.Class A61M 1/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
1Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
Appl.No PCT/MX2019/050012 Applicant ROBLERO RIVERA, Carlos Alexander Inventor ROBLERO RIVERA, Carlos Alexander
The invention relates to a filter for collecting, processing and injecting a graft of fatty tissue that is placed inside a container for collecting fatty tissue, for treatment based on vacuum filtration without losing properties through stress during the centrifuge, in less time and without the need to remove said fatty tissue from the collection container, avoiding exposure to the environment for a second treatment minimising the risk of infection, obtaining favourable results and improving patient recovery with improved results.
10.WO/2020/236626METHODS AND SYSTEMS FOR TREATING MICROBIAL DISEASE
WO 26.11.2020
Int.Class A61K 39/395
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
Appl.No PCT/US2020/033210 Applicant HERZLINGER, George A. Inventor HERZLINGER, George A.
The present disclosure provides methods and systems for treating a biological fluid of a subject suffering from a microbial infection (e.g., a drug-resistant microbial infection). In some embodiments, these methods and systems involve a complement receptor immobilized on, or otherwise associated with a polymer substrate, for example, high surface area particles, membranes, hollow fibers, and/or other porous or non-porous media. In other embodiments, the methods and systems involve a complement receptor present in a dialysate used in a dialyzer for extracting pathogens out of a biological fluid, for example, the blood of a patient.