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1. WO2020182596 - DOSAGE FORM COMPRISING A POLYMERIC MATRIX

Publication Number WO/2020/182596
Publication Date 17.09.2020
International Application No. PCT/EP2020/055810
International Filing Date 05.03.2020
IPC
A61K 9/20 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
20Pills, lozenges or tablets
A23L 5/00 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
5Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
A61K 8/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
A61K 31/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
A61K 36/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
CPC
A23L 5/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
5Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
A61K 36/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 38/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
Applicants
  • EVONIK OPERATIONS GMBH [DE]/[DE]
Inventors
  • MOERS, Christian
  • ENDRES, Thomas
  • MEIER, Christian
  • DEL ROSARIO FERRAND, Jessica
  • SCHATTKA, Jan Hendrik
  • JUNG, Herbert
  • EURICH, Thomas
Agents
  • EVONIK PATENT ASSOCIATION
Priority Data
62/816,60511.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DOSAGE FORM COMPRISING A POLYMERIC MATRIX
(FR) FORME POSOLOGIQUE COMPRENANT UNE MATRICE POLYMÈRE
Abstract
(EN)
The invention is concerned with a dosage form, comprising a polymeric matrix, comprising one or more polymer(s) and a biologically active ingredient, wherein the polymeric matrix comprises 10 % by weight or more of the one or more polymer(s) and wherein the one or more polymer(s) are polymerized from a monomer mixture comprising the monomers (a) 70 to 95 % by weight of 2-ethylhexyl methacrylate (EHMA) and ethyl methacrylate (EMA) or 2-ethylhexyl methacrylate (EHMA) and methyl methacrylate (MMA), (b) 0 to 25 % by weight of a C2 to C6 hydroxy-alkylester of acrylic acid or methacrylic acid, (c) 2.5 to 20 % by weight of a C2 to C8 alkyl ester of acrylic acid or of methacrylic acid with a quaternary cationic group in the alkyl group.
(FR)
L'invention concerne une forme posologique comprenant une matrice polymère, comprenant un ou plusieurs polymères et un ingrédient biologiquement actif, la matrice polymère comprenant 10 % en poids ou plus d'au moins un polymère et au moins un polymère étant polymérisé à partir d'un mélange de monomères ayant les monomères suivants, (a) 70 à 95 % en poids de méthacrylate de 2-éthylhexyle (EHMA) et de méthacrylate d'éthyle (EMA) ou de méthacrylate de 2-éthylhexyle (EHMA) et de méthacrylate de méthyle (MMA), (b) 0 à 25 % en poids d'un hydroxy-alkylester C2 à C6 d'acide acrylique ou d'acide méthacrylique, (c) 2,5 à 20 % en poids d'un ester alkylique C2 à C8 d'acide acrylique ou d'acide méthacrylique avec un groupe cationique quaternaire dans le groupe alkyle.
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