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1. WO2020153734 - PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SQUIRREL FIBROMA VIRUS AND REOVIRUS

Publication Number WO/2020/153734
Publication Date 30.07.2020
International Application No. PCT/KR2020/001053
International Filing Date 22.01.2020
IPC
A61K 35/76 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
76Viruses; Subviral particles; Bacteriophages
A61K 35/765
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
76Viruses; Subviral particles; Bacteriophages
765Reovirus; Rotavirus
A61K 31/7088 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
A61K 45/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • 바이로큐어 주식회사 VIROCURE, INC. [KR]/[KR]
Inventors
  • 김만복 KIM, Man-Bok
  • 조진아 CHO, Jin Ah
  • 송기훈 SONG, Ki-Hoon
Agents
  • 이명진 LEE, Myoung-Jin
Priority Data
10-2019-000976325.01.2019KR
10-2019-017916031.12.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SQUIRREL FIBROMA VIRUS AND REOVIRUS
(FR) COMPOSITION PHARMACEUTIQUE POUR LA PRÉVENTION OU LE TRAITEMENT DU CANCER, COMPRENANT UN VIRUS DE FIBROME D'ÉCUREUIL ET UN RÉOVIRUS
(KO) 다람쥐 섬유종 바이러스 및 리오바이러스를 포함하는 암 예방 또는 치료용 약학적 조성물
Abstract
(EN)
The present invention relates to a use of squirrel fibroma virus and a reovirus for preventing or treating cancer. The squirrel fibroma virus and the reovirus of the present invention, or a pharmaceutical composition comprising a biological sample treated with the two viruses have the effect of inhibiting the growth of cancer cells by exhibiting tumor lytic activity by specifically infecting the cancer cells, without affecting normal cells of a human.
(FR)
La présente invention concerne une utilisation d'un virus de fibrome d'écureuil et un réovirus pour la prévention ou le traitement du cancer. Le virus de fibrome d'écureuil et le réovirus selon la présente invention, ou une composition pharmaceutique comprenant un échantillon biologique traité avec les deux virus, ont pour effet d'inhiber la croissance de cellules cancéreuses en présentant une activité lytique tumorale en infectant spécifiquement les cellules cancéreuses, sans affecter les cellules normales chez l'homme.
(KO)
본 발명은 다람쥐 섬유종 바이러스 및 리오바이러스의 암 예방 또는 치료 용도에 관한 것이다. 본 발명의 다람쥐 섬유종 바이러스 및 리오바이러스, 또는 상기 두 바이러스로 처리된 생물학적 샘플을 포함하는 약학적 조성물은 인간의 정상세포에는 아무런 영향을 미치지 않으면서 암세포에 특이적으로 감염하여 종양용해 활성을 나타내 암세포의 성장을 억제하는 효능이 있다.
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