Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020127975 - NATIVE DELIVERY OF BIOMOLECULES INTO PLANT CELLS USING IONIC COMPLEXES WITH CELL-PENETRATING PEPTIDES

Publication Number WO/2020/127975
Publication Date 25.06.2020
International Application No. PCT/EP2019/086682
International Filing Date 20.12.2019
IPC
C12N 15/82 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
82for plant cells
Applicants
  • BASF PLANT SCIENCE COMPANY GMBH [DE]/[DE]
  • RIKEN [JP]/[JP]
Inventors
  • BAUER, Joerg
  • LAI, Fang-Ming
  • BERNASCONI, Paul
  • RODRIGUEZ, Marianela
  • CARDOZA, Vinitha
  • NUMATA, Keiji
  • GUO, Boyang
Agents
  • BASF IP ASSOCIATION
Priority Data
62/782,81620.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NATIVE DELIVERY OF BIOMOLECULES INTO PLANT CELLS USING IONIC COMPLEXES WITH CELL-PENETRATING PEPTIDES
(FR) ADMINISTRATION NATIVE DE BIOMOLÉCULES DANS DES CELLULES VÉGÉTALES À L'AIDE DE COMPLEXES IONIQUES AVEC DES PEPTIDES DE PÉNÉTRATION CELLULAIRE
Abstract
(EN)
The invention relates to a complex comprising a first component: (i) a carrier peptide comprising a cell-penetrating sequence and a polycation sequence: and a second component (ii) a ribonucleic acid (RNA), PNA and/or protein, wherein the carrier peptide is a cyclic peptide comprising at least 2 cysteine residues bridged by a disulphide bond.
(FR)
L'invention concerne un complexe comprenant un premier composant : (i) un peptide porteur comprenant une séquence de pénétration cellulaire et une séquence de polycations; et un second composant (ii) : un acide ribonucléique (ARN), un PNA et/ou une protéine, le peptide porteur étant un peptide cyclique comprenant au moins 2 résidus de cystéine pontés par une liaison disulfure.
Latest bibliographic data on file with the International Bureau