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1. CN111297989 - Chinese herbal compound prescription for treating novel coronavirus

Office China
Application Number 202010234228.2
Application Date 30.03.2020
Publication Number 111297989
Publication Date 19.06.2020
Publication Kind A
IPC
A61K 36/88
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
88Liliopsida (monocotyledons)
A61P 31/14
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
12Antivirals
14for RNA viruses
CPC
A61K 36/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
A61K 36/185
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
A61K 36/32
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
32Burseraceae (Frankincense family)
A61K 36/48
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
A61K 36/489
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
489Sophora, e.g. necklacepod or mamani
A61K 36/744
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
74Rubiaceae (Madder family)
744Gardenia
Applicants BEIJING HOSPITAL OF T.C.M AFFILIATED TO CAPITAL UNIVERSITY OF MEDICINE SCIENCES
首都医科大学附属北京中医医院
Inventors GUO YUHONG
郭玉红
LIU QINGQUAN
刘清泉
XU XIAOLONG
徐霄龙
FAN HUAHAO
范华昊
TONG YIGANG
童贻刚
Agents 北京科亿知识产权代理事务所(普通合伙) 11350
Title
(EN) Chinese herbal compound prescription for treating novel coronavirus
(ZH) 一种治疗新型冠状病毒的中药复方
Abstract
(EN)
The invention discloses a Chinese herbal compound prescription for treating novel coronavirus, and belongs to the field of traditional Chinese medicines. A strain of the novel coronavirus is isolatedand cultivated, named xCov, and is deposited in the China General Microbiological Culture Collection Center with the deposit number of CGMCC NO.19295 on date of February 14, 2020, and the taxonomic name is Coronavirus. The virus has 92% homology with the S protein of 2019-nCoV, is very safe, and can be used for drug screening and evaluation, vaccine screening and evaluation of 2019-nCoV virus andpreparation of attenuated and inactivated vaccines. The xCov is used as a model to screen out the Chinese herbal compound prescription with obvious inhibitory effect on the xCov, and a new direction and idea are provided for the treatment of 2019-nCoV.

(ZH)
本发明公开了一种治疗新型冠状病毒的中药复方,属于中药领域。本发明分离培养出了一株新型冠状病毒,命名为xCov,已保藏于中国微生物菌种保藏管理委员会普通微生物中心,保藏编号:CGMCC NO.19295,保藏日期:2020年2月14日,分类学命名:冠状病毒。该病毒与2019‑nCoV的S蛋白同源性达92%,而且非常安全,可用于2019‑nCoV病毒的药物筛选与评价、疫苗筛选与评价、减毒及灭活疫苗的制备。本发明利用xCov作为模型,筛选出对其具有明显抑制作用的中药复方,为2019‑nCoV的治疗提供了新的方向和思路。